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Example question00:34

A 4-year-old boy is brought to the emergency department with dark urine and jaundice two days after eating fava beans. Hemoglobin is 7.2 g/dL, reticulocytes are 9%, and the smear shows bite cells. A G6PD activity assay sent today is normal. What is the most appropriate way to settle the diagnosis?

ADirect antiglobulin test
BHemoglobin electrophoresis
CRepeat G6PD assay after recovery
DOsmotic fragility test
Correct — young red cells can make the assay falsely normal during acute hemolysis.
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